WEB COAG: Synopsis of Coagulopathy and Therapeutic Modalities

• Factor XII Deficiency, Hereditary:
• Prekalikrein Deficiency
• Factor XI Deficiency
• Factor IX Deficiency (Hemophilia B)
• Factor VIII Deficiency (Hemophilia A)
• Acquired Factor VIII Inhibitor in Hemophilia A
• vonWillebrand's Disease, type I
• vonWillebrand's Disease, type IIA
• vonWillebrand's Disease, type IIB
• vonWillebrand's Disease, type III
• Factor VII Deficiency
• Factor X Deficiency
• Factor V Deficiency
• Afibrinogenemia
• Hypofibrinogenemia
• Dysfibrinogenemia
• Factor XIII Deficiency
• Antithrombin III Deficiency
• Alpha-2 Antiplasmin Deficiency
• Protein C Deficiency
• Factor V Leiden
• Prothrombin Mutation

• Coagulopathy in Vitamin K Deficiency
• Spontaneous Factor VIII Inhibitor
• Coagulopathy in Liver Failure
• Disseminated Intravascular Coagulation
• Lupus Anticoagulant
• Coagulopathy in Multiple Myeloma
• Coagulopathy in Polycythemia Vera
• Coagulopathy following Coronary Artery Bypass
• Antithrombin III Deficiency
• Factor XII Deficiency in Nephrotic Syndrome

• Glanzmann's Thrombasthenia
• Bernard Soulier Syndrome
• Platelet Storage Pool Disease

• Immune Thrombocytopenic Purpura
• Platelet Dysfunction secondary to Medication
• Thrombotic Thrombocytopenic Purpura
• Heparin-Induced Thrombocytopenia
• Neonatal Alloimmune Thrombocytopenia
• Platelet Dysfunction secondary to Renal Insufficiency

• Coagulation Profile associated with Heparin Therapy
• Coagulation Profile associated with Coumadin Therapy
• Coagulation Profile associated with Streptokinase Therapy

• Fresh Frozen Plasma
• Cryoprecipitate
• Platelets
• 1-Deamino-8-D-Arginine Vasopressin (DDAVP)
• Prothrombin Complex
• Epsilon-Aminocaproic Acid (EACA)
• Factor Concentrates (VIII, IX)

Calculating Units of Cryoprecipitate for Fibrinogen

View Coagulation Cascade Diagram

View Platelet Aggregation Patterns for Platelet Disorders

---

View Flow Chart for Work-up of Prolonged PTT